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XELJANZ/XELJANZ XR is used to treat adults with moderately to severely active rheumatoid arthritis in which methotrexate did not work well. XELJANZ/XELJANZ XR may be used as a single agent or in combination with methotrexate (MTX) or other .
Xeljanz works by inhibiting the JAK proteins, which participate in several signaling mechanisms related to the immune response that causes pain, tenderness and inflammation. The use of Xeljanz to treat moderate-to-severe RA is approved in more than 50 .
There were some preclinical data suggesting that it might influence c-MYC, so we're combining that with dose-suggested EPOCH-R. That became a regimen that we use, that we tended to use that or Hyper-CVAD, because there was a sense that it was more.
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Arjun Balar, MD, recently sat down with Targeted Oncology to discuss immunotherapy treatment considerations and decisions for patients with advanced bladder cancer based on 3 case scenarios. Balar. Most commonly used in this setting would be a.